Gene interactions and pathways from curated databases and text-mining

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ESAT — IL2

Text-mined interactions from Literome

Wang et al., J Immunol 2009 : ESAT-6 also inhibited T cell production of IL-17 and TNF-alpha but not IL-2
Samten et al., Tuberculosis (Edinb) 2009 : ESAT-6 also inhibited T-cell production of IL-17 and TNF-a, but not IL-2
Wang et al., J Immunol 2012 : ESAT-6 inhibited LPS/CD40L induced DC expression of costimulatory molecules, reduced DC-stimulated allogeneic T cell proliferation and IL-2 and IFN-? production, and enhanced IL-17 production