Gene interactions and pathways from curated databases and text-mining

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CD81 — IFNG

Text-mined interactions from Literome

Tseng et al., J Exp Med 2002 : In this study, we show that CD81 cross linking via immobilized E2 or mAbs specific for CD81 inhibits not only non major histocompatibility complex restricted cytotoxicity mediated by NK cells but also interferon (IFN)-gamma production by NK cells after exposure to interleukin (IL)-2, IL-12, IL-15, or CD16 cross linking
Li et al., J Leukoc Biol 2004 : Ligation of CD81 on NK cells inhibits IFN-gamma production and results in decreased anti-HCV activity
Crotta et al., J Hepatol 2010 : We found that immobilized HCVcc, unlike soluble HCVcc, inhibited IFN-gamma production by interleukin (IL)-12 activated NK cells, and that this effect was mediated by engagement of cellular CD81 by HCV-virion displayed E2