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CD81 — IFNG
Text-mined interactions from Literome
Tseng et al., J Exp Med 2002
:
In this study, we show that
CD81 cross linking via immobilized E2 or mAbs specific for CD81
inhibits not only non major histocompatibility complex restricted cytotoxicity mediated by NK cells but also
interferon (IFN)-gamma production by NK cells after exposure to interleukin (IL)-2, IL-12, IL-15, or CD16 cross linking
Li et al., J Leukoc Biol 2004
:
Ligation of
CD81 on NK cells
inhibits IFN-gamma production and results in decreased anti-HCV activity
Crotta et al., J Hepatol 2010
:
We found that immobilized HCVcc, unlike soluble HCVcc, inhibited
IFN-gamma production by interleukin (IL)-12 activated NK cells, and that this effect was
mediated by engagement of cellular
CD81 by HCV-virion displayed E2