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HSP90AA1 — IL1A
Text-mined interactions from Literome
Kanzaki et al., Biochem Biophys Res Commun 2003
:
Telomerase upregulates expression levels of
interleukin (IL)-1alpha , IL-1beta, IL-6, IL-8, and granulocyte-macrophage colony stimulating factor in normal human fibroblasts
Broemer et al., Oncogene 2004
(Inflammation...) :
Short-time inhibition of
Hsp90 resulted in impaired IKK kinase activation by TNFalpha,
IL-1beta or phorbolester PMA
Hsu et al., Mol Pharmacol 2007
:
In addition,
Hsp90 is important for IL-1 protein translation,
plays a minor role in
IL-1 mRNA transcription, and is involved in nuclear factor-kappaB activation and the phosphorylation and activation of p38, c-Jun NH2-terminal kinase, and extracellular signal regulated kinase ; however, Hsp90 plays a more important role in LPS stimulated p38 activation