Gene interactions and pathways from curated databases and text-mining

◀ Back to GNG5

GCG — GNG5

Pathways - manually collected, often from reviews:

  • Reactome Reaction: GNG5 → GCG (reaction)

Text-mined interactions from Literome

Wasserman et al., Am J Physiol 1989 : In conclusion, in the dog, the exercise induced rise in glucagon 1 ) controls approximately 65 % of the increase in Ra, 2 ) increases hepatic glycogenolysis and GNG , and 3 ) enhances GNG by stimulating precursor extraction by the liver and precursor conversion to glucose within the liver
Cherrington et al., J Clin Invest 1978 (Diabetes Mellitus, Experimental...) : It can be concluded that ( a ) the effect of relative hyperglucagonemia on GP is short lived ; ( b ) the waning of the effect of glucagon is attributable solely to a diminution of glycogenolysis because GNG remains stimulated ; ( c ) basal glucagon markedly enhances the GNG stimulation apparent after induction of insulin deficiency ; and ( d ) basal glucagon worsens the hyperglycemia pursuant on the induction of insulin deficiency both by triggering an initial overproduction of glucose and by maintaining the basal production rate thereafter