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AKT1 — PGF

Text-mined interactions from Literome

Selvaraj et al., Blood 2003 (Anemia, Sickle Cell) : PlGF also induced transient phosphorylation of AKT
Bellik et al., Br J Pharmacol 2005 : In cultured rat VSMCs exposed to hypoxia, PlGF increased the phosphorylation of protein kinase B ( Akt ), p38 and STAT3 ; activation of STAT3 was higher than that of other kinases
Okuyama et al., J Biol Chem 2006 : MSC in which HIF-1 activity was inhibited by a dominant negative or RNA interference approach expressed markedly reduced levels of VEGFR1 and failed to migrate or activate AKT in response to VEGF or PLGF
Tveteraas et al., J Exp Clin Cancer Res 2012 (Carcinoma, Hepatocellular...) : In the MH1C1 hepatocarcinoma cells, stimulation with PGE2 or PGF2a caused phosphorylation of the EGFR, Akt , and ERK, which could be blocked by the EGFR tyrosine kinase inhibitor gefitinib
Tu et al., J Cell Physiol 2013 (Arthritis, Rheumatoid...) : Transfection of dominant negative Akt or application of PI3K inhibitorLY294002 significantly inhibited p-Tyr705-STAT3, p-Ser727-STAT3, and PLGF expression, indicating that Akt is involved in JAK3/STAT3/PLGF signaling cascade
Kunapuli et al., J Biol Chem 1998 (Cardiomegaly) : Both PGF2alpha and 8,12-iso-iPF2alpha-III activate the p70S6 kinase ( p70 ( S6K ) ), but not Akt , downstream of phosphatidylinositol-3-kinase (PI3K)