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CDC42 — PTGS2
Text-mined interactions from Literome
Hahn et al., Biochem J 2002
:
Role of Rac and
Cdc42 in lysophosphatidic acid mediated
cyclo-oxygenase-2 gene expression ... By exclusion of RhoA and non-specific cytoskeletal effects, the results in the present study indicate an important
role for Rac and/or
Cdc42 in pertussis toxin-sensitive LPA mediated
Cox-2 induction
Schmeck et al., Inflammation 2003
:
Therefore,
RhoA/Rac1/Cdc42 contribute to NF-kappaB dependent LPS- and TNFalpha induced expression of
PGHS-2 in EC but had no effect on the activity of expressed COX-1 and COX-2
Zaric et al., J Biol Chem 2005
:
We have previously demonstrated that endothelial cell
COX-2 is
required for integrin alphaVbeta3 dependent activation of Rac-1 and
Cdc-42 and for endothelial cell spreading, migration, and angiogenesis ( Dormond, O., Foletti, A., Paroz, C., and Ruegg, C. ( 2001 ) Nat