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CDC42 — ITGB2

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CDC42 → ITGB2 (increases, ITGB2 Activity, CDC42 Activity)
  Evidence: beta2 integrins induced stimulation of Cdc42

Text-mined interactions from Literome

Weineisen et al., J Immunol 2004 : Furthermore, inhibition of CD11b/CD18 receptor engagement or tyrosine kinase activity blocked the DeltaM5 induced activation of Cdc42 as well as the killing of these bacteria
Nilsson et al., Eur J Immunol 2005 : Inhibition of CD11b/CD18 , but not of CD32, the major neutrophil signaling Fc receptor, prevented Streptococcus induced NADPH oxidase dependent respiratory burst, and blocking of C3b/iC3b formation inhibited Streptococcus induced activation of Cdc42 , a small GTPase critically involved in transmitting pro-inflammatory signals to the cytoskeleton