◀ Back to MAPK9
DUSP16 — MAPK9
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
MAPK9
→
DUSP16
(directlyDecreases, DUSP16 Activity, MAPK9 Activity)
Evidence: DUSP8, DUSP10 and DUSP16 make up the third subgroup as they preferentially recognize JNK, p38 or both, respectively
-
KEGG MAPK signaling pathway:
DUSP1/DUSP10/DUSP14/DUSP16/DUSP2/DUSP22/DUSP3/DUSP4/DUSP5/DUSP6/DUSP7/DUSP8/DUSP9
→
MAPK10/MAPK8/MAPK9
(protein-protein, inhibition)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
DUSP16
—
MAPK9
(physical association, affinity chromatography technology)
Tanoue et al., J Biol Chem 2001
-
IRef Hprd Interaction:
MAPK9
—
DUSP16
(in vitro)
Tanoue et al., J Biol Chem 2001
-
IRef Hprd Interaction:
MAPK9
—
DUSP16
(in vivo)
Tanoue et al., J Biol Chem 2001
-
IRef Innatedb Interaction:
MAPK9
—
DUSP16
(unknown, -)
Mooney et al., J Biol Chem 2004*
-
IRef Innatedb Interaction:
MAPK9
—
DUSP16
(unknown, -)
Tanoue et al., J Biol Chem 2001
-
IRef Ophid Interaction:
MAPK9
—
DUSP16
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Givant-Horwitz et al., Gynecol Oncol 2004
(MAP Kinase Signaling System...) :
The objective of the present study was to investigate the expression and clinical role of
dual-specificity phosphatases ( DUSP ) ,
inhibitors of
MAPK signaling, in ovarian cancer cells at this site
Kumabe et al., Microbiol Immunol 2010
:
Activation of
MAPK is negatively
regulated by
DUSP , which dephosphorylate the phosphothreonine and phosphotyrosine residues