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AHSA1 — MAP3K4
Text-mined interactions from Literome
Abell et al., Mol Cell Biol 2005
(MAP Kinase Signaling System...) :
Together, these data demonstrate
MEKK4 regulation of
p38 and that substrates downstream of p38 control cellular homeostasis ... The findings are the first demonstration that
MEKK4 regulated
p38 activity is critical for neurulation
Keil et al., Cell Death Differ 2013
:
Thus, we show for the first time that Atg5 activity is controlled by phosphorylation and, moreover, that the spatial
regulation of
p38 by
Gadd45ß/MEKK4 negatively regulates the autophagic process
Warr et al., Dev Cell 2012
(Gonadal Dysgenesis, 46,XY...) :
Taken together, our data suggest a requirement for GADD45? in promoting
MAP3K4 mediated activation of
p38 MAPK signaling in embryonic gonadal somatic cells for testis determination in the mouse