UCSC Genome Browser Gene Interaction Graph

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to MMP1

CCL2 — MMP1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Hprd Interaction: MMP1 — CCL2 (in vitro) McQuibban et al., Blood 2002, Proost et al., J Immunol 1998 *
IRef Hprd Interaction: MMP1 — CCL2 (in vivo) McQuibban et al., Blood 2002, Proost et al., J Immunol 1998 *

Text-mined interactions from Literome

Zhang et al., J Leukoc Biol 2006 (Coronary Artery Disease) : The objective of this study was to compare the individual and combined effect of CRP and ox-LDL on human monocyte MMP-1 and the role of MCP-1 in this effect
Chen et al., Regul Toxicol Pharmacol 2011 : MMP-1 mRNA expression is up-regulated by elevated cysteine-rich 61 (CYR61) and monocyte chemoattractant protein-1 ( MCP-1 ) via action of transcription factor AP-1 ... Taken together, CDP inhibits UVB induced MMP-1 expression in skin fibroblasts by suppressing expression of AP-1 and CYR61 and MCP-1 production
Park et al., The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2011 : MMP inhibitors, such as doxycycline, minocycline, and batimastat, significantly reduced the cerebral infarct size, and the expressions of monocyte chemotactic protein-1 (MCP-1) , tumor necrosis factor-a (TNF-a), and indoleamine 2,3-dioxygenase (IDO)