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DDX58 — TNF
Text-mined interactions from Literome
Matikainen et al., J Virol 2006
:
IFN-alpha and
TNF-alpha induced the expression of the
RIG-I , TLR3, MyD88, TRIF, and IRF7 genes, whereas no detectable TLR7 and TLR8 was seen in A549 cells
Kitamura et al., J Dermatol Sci 2007
(Psoriasis) :
The present study was designed to investigate the
effects of interferon (IFN)-gamma and
tumor necrosis factor (TNF)-alpha on
RIG-I expression in human keratinocytes, and the expression of RIG-I in skin lesions of psoriasis vulgaris, in which IFN-gamma and TNF-alpha are considered to be involved in its pathogenesis
Matsumiya et al., J Immunol 2007
(Uterine Cervical Neoplasms) :
Our findings support a sequential mechanism whereby
TNF-alpha leads to stabilization of IFN-epsilon mRNA, increased IFN-epsilon synthesis, engagement of type I IFNRs, increased STAT1 expression and phosphorylation, and up-regulation of
RIG-I expression
Wang et al., J Immunol 2008
(Salmonella Infections, Animal) :
Interference of RIG-I expression short interfering RNA represses the expression of LPS induced TNF-alpha, whereas over-expression of
RIG-I leads to the activation of
TNF-alpha promoter and the induction of TNF-alpha expression ... Thus,
RIG-I plays a key role in the expression of
TNF-alpha in macrophages in response to LPS stimulation, mainly for the late phase LPS induced expression of TNF-alpha
Imaizumi et al., Immunol Lett 2009
(Arthritis, Rheumatoid) :
RNA interference against interferon (IFN)-beta abolished the
TNF-alpha induced
RIG-I expression
Kawaguchi et al., Immunol Lett 2009
(Colonic Neoplasms) :
RIG-I was constitutively expressed in the epithelial cell lines HT-29, and IFN-gamma and
TNF-alpha enhanced the RIG-I expression in a dose dependent manner