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EGF — MYL2
Text-mined interactions from Literome
Even-Faitelson et al., Cell Signal 2005
:
Furthermore, cells expressing the dominant negative mutant exhibited an increase in
EGF dependent
myosin light chain phosphorylation and diminished chemotaxis towards EGF
Even-Faitelson et al., Mol Biol Cell 2006
:
Here we show that
myosin II-B , an important cytoskeletal protein, resides in a complex with p21 activated kinase 1 (PAK1) and atypical protein kinase C (PKC) zeta ( aPKCzeta ) and that the interaction between these proteins is
EGF dependent
Schneider et al., Mol Biol Cell 2009
:
These results suggest that
EGF mediated activation of
myosin-II acts as a mechanical signal to promote a cycle of paxillin phosphorylation/dephosphorylation that mediates a cycle of adhesion strengthening and weakening that delays cell retraction