Rotstein et al., Invest Ophthalmol Vis Sci 2003
:
Glia derived neurotrophic factor , a photoreceptor trophic factor, only slightly increased Bcl-2 expression and did not protect photoreceptors from oxidative damage
Saini et al., J Neurochem 2004
:
In addition, transient transfection experiments using various regions of the Bcl-2 promoter and mutation of the CRE site indicate a direct role of CREB in regulating Bcl-2 gene activity in response to NT-3