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CD34 — IL16

Text-mined interactions from Literome

Drouet et al., Stem Cells 2001 : We showed in a nonhuman primate model of autologous peripheral blood stem and progenitor cell transplantation that cell cycle activation of CD34 ( + ) cells in the presence of stem cell factor + FLT3-ligand + thrombopoietin + interleukin 3 ( six days of culture ) which induced G1 and S/G2/M cell amplification ( G0 : 6.1 % +/- 2.8 % ; G0/G1 : 64.2 % +/- 7.2 % ; S/G2/M : 30.4 % +/- 7.3 % respectively of expanded CD34 ( + ) cells on average ) resulted in the acceleration of short-term granulocyte recovery
Della Bella et al., Blood 2004 : Here, we show that IL-16 added to a basal cocktail comprised of granulocyte-macrophage colony stimulating factor ( GM-CSF ), IL-4, Flt-3 ligand (Flt3L), and tumor necrosis factor alpha (TNF-alpha) does induce the CD34 ( + ) hematopoietic cells to proliferate in vitro and to differentiate into phenotypically and functionally mature DCs