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IRAK4 — LEP

Text-mined interactions from Literome

Hosoi et al., Biochem Biophys Res Commun 2002 : Leptin induces IL-1 receptor antagonist expression in the brain
Gonzalez et al., Mol Hum Reprod 2003 : Leptin stimulated IL-1 antagonist ( IL-1Ra ), IL-1beta secretion and expression of IL-1 receptor type I (IL-1R tI) in both cell types
Wisse et al., Brain Res 2007 (Body Weight) : We hypothesized that IL1 receptor signaling is required for exogenously administered leptin to cause anorexia and weight loss, but not for physiological effects of endogenous leptin signaling on energy balance
Johnston et al., Br J Dermatol 2008 (Chronic Disease...) : In vitro, both leptin and resistin could induce CXCL8 and tumour necrosis factor-alpha production by blood monocytes, and leptin could additionally induce IL-1beta and IL-1 receptor antagonist production