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Blero et al., Biochem Biophys Res Commun 2001
:
Overexpression of SHIP2 led to a decrease of the insulin dependent PIP3 production as well as Akt/PKB activation and MAPK stimulation
Choi et al., Oncogene 2002
(MAP Kinase Signaling System...) :
Although SHIP2 expression resulted in suppression of interleukin-6 mediated mitogen activated protein kinase activation, expression of SHIP and SHIP2 in a PTEN-null myeloma line did not suppress Akt activity
Jurynec et al., Dis Model Mech 2010
(Obesity) :
Loss of Ship2a leads to an increased and expanded expression of outputs of FGF mediated signaling, including FGF dependent gene expression and activated mitogen activated protein kinase ( MAPK ) signaling