We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to TP53

NOTCH3 — TP53

Text-mined interactions from Literome

Laws et al., Eur J Immunol 2004 : We hypothesize that p53 regulates Notch activity during T cell development
Beverly et al., Cancer Res 2005 (Cell Transformation, Neoplastic...) : Therefore, it is the suppression of p53 that provides the Achilles heel for Notch induced tumors, as activation of p53 in the presence of Notch signaling drives tumor regression
Alimirah et al., Neoplasia (New York, N.Y.) 2007 (Neoplasms) : Notably, p53 differentially regulated the expression of Notch family members : expression of Notch2 and Notch4 was not induced by p53
Ban et al., Cancer Res 2008 (Sarcoma, Ewing) : EWS-FLI1 suppresses NOTCH activated p53 in Ewing 's sarcoma ... Conversely, forced expression of JAG1, activated NOTCH3 , or HEY1 induced p53 and p21 ( WAF1/CIP1 )