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CDC42 — MYLIP

Text-mined interactions from Literome

Lal et al., Mol Cell 2009 : In fact, miR-24 regulates expression of E2F2, MYC, AURKB, CCNA2, CDC2 , CDK4, and FEN1 by recognizing seedless but highly complementary sequences
Liu et al., Int J Cancer 2011 (Colorectal Neoplasms) : miR-137 could significantly suppress Cdc42 3 ' UTR luciferase-reporter activity, and this effect was not detectable when the putative 3 ' UTR target-site was mutated ... Consistent with the results of the reporter assay, ectopic expression of miR-137 reduced both mRNA and protein expression levels of Cdc42 and mimicked the effect of Cdc42 knockdown in inhibiting proliferation, inducing G1 cell cycle arrest, and blocking invasion of the colorectal cancer cells, whereas anti-miR-137 expression led to the opposite effect
Cui et al., Cancer Biol Ther 2010 (Breast Neoplasms) : Thus, we conclude that miR-520b and miR-520e contribute to CDC in breast cancer cells via directly targeting the 3'UTR of CD46
Chen et al., Dig Dis Sci 2011 (Carcinoma...) : Epigenetic silencing of miR-137 induced an up-regulation of its targets, Cdc42
Ma et al., Beijing Da Xue Xue Bao 2011 (Ovarian Neoplasms) : miR-449b and miR-34c resulted in cell cycle arrests and down-regulation of CDK6, CDC25A and CyclinA in high malignant ovarian cancer cell line SKOV3-ipl
Tang et al., Curr Cancer Drug Targets 2012 (Brain Neoplasms...) : LRRC4 overexpression inhibited glioma cell invasion through miR-185 mediated CDC42 and RhoA direct regulation and VEGFA indirect regulation
Li et al., Biochem Biophys Res Commun 2013 (Cell Transformation, Neoplastic...) : miR-330 regulates the proliferation of colorectal cancer cells by targeting Cdc42 ... To sum up, our results establish a role of miR-330 in negatively regulating Cdc42 expression and colorectal cancer cell proliferation
Wang et al., Hepatology 2013 (Carcinoma, Hepatocellular...) : Additionally, miR-195 down-regulation led to increases in VAV2 and CDC42 expression, which stimulated VAV2/Rac1/CDC42 signaling and lamellipodia formation and thereby facilitated the metastasis of HCC cells
Furuta et al., PloS one 2013 (Carcinoma, Hepatocellular...) : Among the candidates, we successfully identified CCNE1, CDC25A , CCND3, CDK4, and BTRC as direct targets for miR-497 and miR-195
Shi et al., PloS one 2013 (Colitis...) : Finally, we found that miR-21 regulated the intestinal barrier function through modulating the expression of RhoB and CDC42