Gene interactions and pathways from curated databases and text-mining

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MAPK11 — NFATC1

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: NFATC1 — MAPK11 (interaction, mapped from kegg_pathways)
  • STRING interaction: NFATC1 — MAPK11 (interaction, mapped from kegg_pathways)
  • STRING interaction: MAPK11 — NFATC1 (interaction, mapped from grid kegg_pathways mint intact)
  • STRING interaction: MAPK11 — NFATC1 (interaction, mapped from grid kegg_pathways mint intact)

Text-mined interactions from Literome

Wu et al., Mol Cell Biol 2003 : Fourth, p38 MAPK promoted the interaction of NFATc with the coactivator CREB binding protein ... All together, the overall effect of p38 MAPK on NFATc in T cells is clear activation
Holsinger et al., Curr Biol 1998 : Activation of Jun N-terminal kinase or stress activated kinase ( JNK or SAPK ) and mitogen activated protein kinase ( MAPK ) and the induction of the transcription factor NF-ATc1 and egr-1 genes was normal