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BECN1 — TP53

Text-mined interactions from Literome

Park et al., Biochem Biophys Res Commun 2009 : Here we report that, in the JNK dependent autophagic cell death of HCT116 cells induced by an agonistic single chain variable fragment antibody, HW1, against human death receptor 5 (DR5), JNK activation upregulated Beclin-1 expression and induced Bcl-2 and p53 phosphorylation
Liu et al., Cell 2011 : Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13
Liu et al., J Pharmacol Sci 2012 (Lung Neoplasms) : Moreover, ERK activation upregulated Beclin-1 expression through induction of Bcl-2 phosphorylation, but p53 did not induce Bcl-2 phosphorylation
Dai et al., International journal of molecular sciences 2012 : RT-PCR revealed that the expression levels of p53, Bax and Beclin 1 were up-regulated in a dose dependent manner, indicating that Beclin 1 was involved in Rapa induced autophagy and Rapa induced apoptosis as well as p53 up-regulation in PC-2 cells