Ghule et al., J Cell Physiol 2009
(Aneuploidy...) :
Transcription is controlled at the G1/S phase transition by the Cyclin E/CDK2 mediated induction of p220 ( NPAT ) /HiNF-P complexes at subnuclear domains designated Histone Locus Bodies ( HLBs ) that associate with histone gene clusters
Xie et al., Proc Natl Acad Sci U S A 2009
:
Here, we show that the downstream CDK dependent cell cycle effector HINFP is genetically required and, in contrast to the CDK2/cyclin E complex, can not be compensated