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SETD2 — TGFB1
Text-mined interactions from Literome
Sánchez-Elsner et al., J Mol Biol 2004
(Anoxia) :
In the present work, a cooperative interaction between hypoxia,
mediated by the
HIF-1 complex, and
transforming growth factor-beta ( TGF-beta ), mediated by Smad3/4, was revealed in the Epo gene
Qian et al., Mol Reprod Dev 2004
:
Meanwhile, treatment of normal human cytotrophoblast cells with
TGF-beta1 induced expression of
HIF-1a , the regulated subunit of hypoxia-inducible factor 1, a known transactivator of the VEGF gene
McMahon et al., J Biol Chem 2006
(Inflammation) :
Among others, recent studies indicated that
transforming growth factor ( TGF ) beta increases the expression of the regulatory HIF-1alpha subunit, and
induces HIF-1 DNA binding activity