Gene interactions and pathways from curated databases and text-mining

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SETD2 — TGFB1

Text-mined interactions from Literome

Sánchez-Elsner et al., J Mol Biol 2004 (Anoxia) : In the present work, a cooperative interaction between hypoxia, mediated by the HIF-1 complex, and transforming growth factor-beta ( TGF-beta ), mediated by Smad3/4, was revealed in the Epo gene
Qian et al., Mol Reprod Dev 2004 : Meanwhile, treatment of normal human cytotrophoblast cells with TGF-beta1 induced expression of HIF-1a , the regulated subunit of hypoxia-inducible factor 1, a known transactivator of the VEGF gene
McMahon et al., J Biol Chem 2006 (Inflammation) : Among others, recent studies indicated that transforming growth factor ( TGF ) beta increases the expression of the regulatory HIF-1alpha subunit, and induces HIF-1 DNA binding activity