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GRK7 — SRC

Text-mined interactions from Literome

Fan et al., J Biol Chem 2001 (Carcinoma, Squamous Cell) : Downstream of binding to the receptor, Src phosphorylates and activates G-protein linked receptor kinase 2 ( GRK2 ), a response obligate for agonist induced desensitization
Penela et al., EMBO J 2001 : In this report, we find that beta-arrestin function and Src mediated phosphorylation of GRK2 are critically involved in GRK2 proteolysis
Heijink et al., Am J Physiol Lung Cell Mol Physiol 2005 (Asthma...) : Our data suggest that this is mediated by Src dependent activation of GRK2 , resulting in receptor phosphorylation, binding to beta-arrestin, and a switch from cAMP dependent signaling to activation of the MAPK pathway
Mahavadi et al., Regul Pept 2007 : Cross-regulation of VPAC2 receptor internalization by m2 receptors via c-Src mediated phosphorylation of GRK2