Gene interactions and pathways from curated databases and text-mining

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PIN1 — RELA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Kuboki et al., Am J Physiol Gastrointest Liver Physiol 2007 (Hypothermia...) : Furthermore, it appears that Pin1 promotes NF-kappaB p65 protein stability such that decreased expression of Pin1 during ischemia-reperfusion results in p65 degradation, reduced nuclear translocation of NF-kappaB , and enhanced hepatocellular injury
Peloponese et al., J Virol 2009 : We show here that prolyl isomerase Pin1 is over expressed in HTLV-1 cell lines ; Pin1 binds Tax and regulates Tax induced NF-kappaB activation
Risal et al., Pathol Int 2012 (Drug-Induced Liver Injury...) : In addition, Pin1 overexpression increased NF-kB activity, as evidenced by increased DNA binding
Wang et al., Oncogene 2012 (Breast Neoplasms...) : The effect of FOXC1 on p65/RelA protein stability is mediated by increased expression of Pin1 , a peptidyl-prolyl isomerase