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CXCR4 — IL7

Text-mined interactions from Literome

Llano et al., J Virol 2001 (Acquired Immunodeficiency Syndrome) : IL-7 induced T-cell proliferation and up-regulated CXCR4 expression in peripheral blood mononuclear cells in vitro
Pedroza-Martins et al., J Virol 2002 (HIV Infections) : IL-2 and IL-4 together increased expression of CXCR4 and CCR5 in this population, whereas IL-4 and IL-7 increased CXCR4 but not CCR5 expression
Schmitt et al., J Virol 2003 : This positive regulation of CXCR4 by IL-7 in mature CD4 ( + ) thymocytes correlates with their high capacity to favor X4 virus replication compared with intermediate thymocytes or peripheral blood mononuclear cells