Shin et al., Mol Biol Cell 2001
:
In NMuMG and 4T1 mammary epithelial cells, transforming growth factor beta ( TGF beta ) induced phosphorylation and cytoplasmic retention of the Forkhead factor FKHRL1 , while reducing FHKRL1 dependent transcriptional activity
Kim et al., BMB Rep 2008
(Carcinoma, Hepatocellular...) :
This work aimed to elucidate the involvement of FoxO3a in transforming growth factor-beta1 ( TGF-beta1 ) -induced apoptosis in FaO rat hepatoma cells ... TGF-beta1 caused a time dependent activation of FoxO3a and a subsequent increase in FoxO response-element containing luciferase reporter activity, which was Akt-sensitive