Gene interactions and pathways from curated databases and text-mining

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AKT2 — PCK1

Text-mined interactions from Literome

Kizelsztein et al., Am J Physiol Endocrinol Metab 2009 (Body Weight...) : Here we show that in H4IIE cell culture, 20HE treatment decreased expression of phosphoenolpyruvate carboxykinase ( PEPCK ) and glucose-6-phosphatase (G6Pase), reduced glucose production, and induced Akt2 phosphorylation sensitive to the phosphoinositide-3 kinase pathway-specific inhibitor LY-294002
Marucci et al., Biochim Biophys Acta 2013 : In addition, GALNT2 down-regulation reduced insulin stimulation of IR, IRS-1 and Akt phosphorylation and insulin inhibition of phosphoenolpyruvate carboxykinase ( PEPCK ) expression, a key neoglucogenetic enzyme