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ATP5O — NQO1

Text-mined interactions from Literome

Guo et al., Cancer Res 2005 (Breast Neoplasms) : Maximal 17-AAG induced ATPase inhibition was observed in the presence of NQO1 and could be abrogated by ES936, showing that 17-AAGH2 was a more potent Hsp90 inhibitor compared with 17-AAG
Guo et al., Mol Pharmacol 2006 : Inhibition of purified yeast Hsp90 ATPase activity was augmented in the presence of NQO1 and abrogated by 5-methoxy-1,2-dimethyl-3- [ ( 4-nitrophenoxy ) methyl- ] indole-4,7-dione ( ES936 ), a mechanism based inhibitor of NQO1, showing that the hydroquinone ansamycins were more potent Hsp90 inhibitors than their parent quinones