Gene interactions and pathways from curated databases and text-mining

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BMP7 — SMN1

Text-mined interactions from Literome

Chalazonitis et al., J Neurosci 2004 : When applied to immunopurified E12 ENS precursors, BMP-2 and BMP-4 induced nuclear translocation of phosphorylated Smad-1 ( Sma and Mad related protein )
Matsui et al., Dev Growth Differ 2008 : During heart development at the gastrula stage, inhibition of bone morphogenetic protein ( BMP ) activity affects the heart specification but does not impair the expression of smooth muscle alpha-actin (SMA) , which is first expressed in the heart mesoderm and recruited into initial heart myofibrils
Zhou et al., Zhongguo Zhong Yao Za Zhi 2010 : BMP-7 significantly inhibited the down-regulation of E-cadherin and the up-regulation of alpha-SMA induced by TGF-beta1 ( P < 0.05 ), and SA-B significantly inhibited the up-regulation of alpha-SMA expression induced by TGF-beta1 ( P < 0.05 ), but not the down-regulation of E-cadherin induced by TGF-beta1
Wang et al., Stem Cells Dev 2012 : Exploring the molecular basis for this effect, we found that restricting cell spreading, reducing ROCK signaling, or inhibiting cytoskeletal tension prevented BMP induced SMA/mothers against decapentaplegic ( SMAD)1 c-terminal phosphorylation, SMAD1 dimerization with SMAD4, and SMAD1 translocation into the nucleus