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MYLK — REN

Text-mined interactions from Literome

Park et al., Am J Physiol 1996 : Furthermore, evidence from our recent studies indicates that myosin light chain kinase (MLCK) might be involved in the inhibition of renin secretion through Ca ( 2+ ) -calmodulin ... In the present study we investigate the possibility that MLCK might mediate the inhibitory action of Ca2+ on renin secretion stimulated by osmotic swelling of renin secretory granules
Park et al., Am J Physiol 1998 : We have recently shown that several putative selective inhibitors of Ca2+-calmodulin dependent myosin light chain kinase (MLCK) , such as ML-9 [ 1- ( 5-chloronaphthalene-1-sulfonyl ) -1H-hexahydro-1,4-diazepine ], reversibly stimulate renin secretion [ C. S. Park, S.-H ... We hypothesized that Ca2+ inhibits renin secretion, via phosphorylation of 20-kDa myosin light chain ( MLC20 ), by activating MLCK