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MAPK3 — SPHK1

Text-mined interactions from Literome

Yadav et al., J Immunol 2006 (Mycobacterium Infections) : Macrophage 's proinflammatory response to a mycobacterial infection is dependent on sphingosine kinase mediated activation of phosphatidylinositol phospholipase C, protein kinase C, ERK1/2 , and phosphatidylinositol 3-kinase
Cheon et al., Biochem Biophys Res Commun 2008 : As a result, inhibition of SPHK by SKI blocked phosphorylation of p38 MAPK , showing that SPHK activation by IL-18 is an upstream signal of p38 MAPK activation
Prakash et al., PloS one 2010 (Mycobacterium Infections, Nontuberculous) : In addition, our results also unraveled a novel regulation of p38MAPK by SphK-1 during M. smegmatis infection and generation of NO in macrophages
Liu et al., Int J Colorectal Dis 2012 (Colonic Neoplasms...) : SphK1 increased the constitutive expression of extracellular signal regulated kinase1/2 ( ERK1/2 ) but reduced the constitutive expression of p38 mitogen activated protein kinase ( MAPK )