Gene interactions and pathways from curated databases and text-mining

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GLI2 — RUNX2

Text-mined interactions from Literome

Shimoyama et al., Mol Biol Cell 2007 : Ihh treatment or Gli2 overexpression also up-regulated the expression of Runx2 , an essential transcription factor for osteoblastogenesis, and enhanced the transcriptional activity and osteogenic action of Runx2 ... Collectively, these results suggest that Ihh regulates osteoblast differentiation of mesenchymal cells through up-regulation of the expression and function of Runx2 by Gli2
Qiu et al., PloS one 2010 : Our findings suggest a role for Pkd1 and Kif3a to counterbalance the regulation of osteogenesis and adipogenesis through differential regulation of Runx2 and PPAR? by Gli2