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CD8A — CXCL10
Text-mined interactions from Literome
Tokuriki et al., J Dermatol Sci 2002
(Dermatitis, Contact) :
Dominant expression of CXCR3 is associated with induced expression of IP-10 at hapten challenged sites of murine contact hypersensitivity : a possible
role for interferon-gamma producing
CD8 ( + ) T cells in
IP-10 expression
Christensen et al., J Immunol 2006
(Lymphocytic Choriomeningitis...) :
In this report, we investigated the
role of
CXCL10 in regulating
CD8 ( + ) T cell mediated inflammation in the virus infected brain
McAllister et al., J Immunol 2006
(Inflammation...) :
These results indicate that the CXCR3 chemokines are part of the host defense response to PC, and that
IP-10 can
direct Tc1
CD8 ( + ) T cell recruitment to the lungs and contribute to host defense against PC even in the absence of CD4 ( + ) T cells
Barral et al., J Autoimmun 2006
(Diabetes Mellitus, Type 1...) :
Not only absence of MHC-I and Fas upregulation, but also resistance to cytokine induced killing of beta-cells and a complete lack of
CXCL-10 ( IP10 ) production in islets
led to a lack of islet infiltration and impaired activation of autoaggressive CD4 ( + ) and
CD8 ( + ) T-cells in these mice