UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

RB1 — SOD1

Text-mined interactions from Literome

Liu et al., Biol Pharm Bull 2011 : Mechanistically, we found that Rb1 could markedly increase intracellular superoxide dismutase ( Cu/Zn SOD/SOD1 ) activity and decrease the malondialdehyde ( MDA ) level in H ( 2 ) O ( 2 ) -treated HUVECs, and suppress the generation of intracellular reactive oxygen species ( ROS ) ... Mechanistically, we found that Rb1 could markedly increase intracellular superoxide dismutase ( Cu/Zn SOD/SOD1 ) activity and decrease the malondialdehyde ( MDA ) level in H ( 2 ) O ( 2 ) -treated HUVECs, and suppress the generation of intracellular reactive oxygen species ( ROS ) ... Consistent with these findings, Rb1 could effectively restore the protein expression of Cu/Zn SOD , which was down-regulated in H ( 2 ) O ( 2 ) treated cells
Li et al., Zhongguo Yao Li Xue Bao 1990 (Coronary Disease...) : PNS 12.5 and 25 mg/L, Rb1 10 mg/L, and Rg1 10 mg/L significantly decreased cardiac CPK release, attenuated myocardial Ca2+ accumulation, reduced malondialdehyde ( MDA ) production and prevented reduction of superoxide dismutase ( SOD ) activity in comparison with the control in perfused isolated rat hearts with global ischemia ( 40 min ) and reperfusion ( 15 min )