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CEBPB — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: CEBPB — TP53 (physical association, anti bait coimmunoprecipitation) Schneider-Merck et al., J Biol Chem 2006*
• IRef Intact Interaction: CEBPB — TP53 (physical association, pull down) Schneider-Merck et al., J Biol Chem 2006*
• IRef Intact Interaction: CEBPB — TP53 (colocalization, fluorescence microscopy) Schneider-Merck et al., J Biol Chem 2006*

Text-mined interactions from Literome

Schneider-Merck et al., J Biol Chem 2006 (Osteosarcoma) : Here we report that C/EBPbeta in turn represses the transcriptional activity of p53 ... Conversely, p53 strongly inhibited binding of endogenous C/EBPbeta from endometrial stromal cells to the C/EBP-responsive region in the decidual prolactin promoter
Ewing et al., Cell Death Differ 2008 : C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf) ... These results indicate that C/EBPbeta represses p53 to promote cell survival downstream of DNA damage and suggest that inhibition of C/EBPbeta may be a target for cancer cotherapy to increase the efficacy of alkylating chemotherapeutic agents
Polson et al., Cell Biol Int 2010 : Our reports, here and previously published, show that repression of p53 by RBP-Jkappa and activation of p53 by C/EBPbeta through differential binding of these two factors indicates a type of co-operative regulation in p53 expression