Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
NFKBIA
→
RAF1
(increases, NFKBIA Activity)
Evidence: C-Raf activates other cellular effectors, but the extent of the interdependence of these actions on MEK1 and MEK2 is not clear. For example, C-Raf activation regulates cytoskeleton formation by modulating the polymerization status of vimentin.165 Cell survival signaling is also regulated by C-Raf, which induces phosphorylation of IkB in the NF-kB-Ik B complex.