Kaneko et al., J Biol Chem 2002
:
The expression of Akt2 activated MyoD-MEF2 transcriptional activity and induced myogenin expression
Wiedmann et al., J Neurosci Res 2005
(Second Messenger Systems) :
However, whether PI3K/Akt regulates MEF2 and the role of MEF2 in IGF-1 mediated survival of neurons are unknown
Nold-Petry et al., J Biol Chem 2009
(MAP Kinase Signaling System) :
Consistent with these observations, activation of the p38alpha/beta and ERK1/2 MAPKs and of protein kinase B/Akt increased in IL-18Ralpha ko MEF , whereas the negative feedback kinase MSK2 was more active in IL-18 ko cells