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ERVK-6 — PTGS2

Text-mined interactions from Literome

Anandalakshmi et al., Science 2000 : The helper component-proteinase ( HC-Pro ) of plant potyviruses suppresses PTGS in plants
Mallory et al., Plant Cell 2001 : Previously, we showed that the helper component-proteinase ( HC-Pro ) of plant potyviruses suppresses PTGS
Khan et al., J Biol Chem 2004 (MAP Kinase Signaling System) : Extracellular matrix induced cyclooxygenase-2 regulates macrophage proteinase expression ... The addition of PGE ( 2 ) to macrophage cultures stimulates their expression of both urokinase-type plasminogen activator and MMP-9, and the selective COX-2 inhibitor NS-398 blocks ECM induced proteinase expression
Pavlovic et al., J Biol Chem 2006 (MAP Kinase Signaling System) : Thus, COX-2 dependent ECM induced proteinase expression is effectively blocked by selective inhibition of EP4, a member of the PGE2 family of receptors
Moriyuki et al., J Pharmacol Sci 2009 : Proteinase activated receptor-2 (PAR2) triggers upregulation of cyclooxygenase-2 (COX-2) and prostaglandin E ( 2 ) ( PGE ( 2 ) ) formation in human alveolar epithelial A549 cells
Sekiguchi et al., J Cell Biochem 2011 : Proteinase activated receptor-1 (PAR1) , upon activation, exerts prostanoid dependent gastroprotection, and increases prostaglandin E ( 2 ) ( PGE ( 2 ) ) release through cyclooxygenase-2 (COX-2) upregulation in rat gastric mucosal epithelial RGM1 cells
Hirota et al., Am J Physiol Gastrointest Liver Physiol 2012 : Epidermal growth factor receptor transactivation is required for proteinase activated receptor-2 induced COX-2 expression in intestinal epithelial cells
Reno et al., Biochem Biophys Res Commun 1998 : In addition, mRNA levels for IL-1, TNF, COX-2 , and iNOS, potential regulators of proteinase/inhibitor expression, have been assessed