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BMP2 — TBX2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Yamada et al., Dev Biol 2000
:
Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development : evidence for
BMP2 induction of
Tbx2
Yang et al., Development 2006
(Heart Defects, Congenital) :
Additionally, we find that
Bmp signaling in Isl1 expressing progenitors is
required for expression of T-box transcription factors
Tbx2 and Tbx3 in heart and limb
Singh et al., Circ Res 2009
:
Unexpectedly, we found in transfection and localization studies in vitro that both Tbx20 and mutant isoforms of Tbx20 unable to bind DNA attenuate
Bmp/Smad dependent activation of
Tbx2 by binding Smad1 and Smad5 and sequestering them from Smad4