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FOXP3 — HMOX1

Text-mined interactions from Literome

Choi et al., Biochem Biophys Res Commun 2005 : In the present work, we demonstrate that Foxp3 can induce heme oxygenase-1 (HO-1) expression and subsequently such regulatory phenotypes as the suppression of nontransfected cells in a cell-cell contact dependent manner as well as impaired proliferation and production of cytokines upon stimulation in Jurkat T cells ... In summary, we demonstrate that Foxp3 induces HO-1 expression and HO-1 engages in Foxp3 mediated immune suppression
Yamashita et al., FASEB J 2006 : HO-1 induction plus DST led to a significant up-regulation of Foxp3 , TGF-beta, IL-10, and CTLA4, which suggests a prominent role for CD4+CD25+ regulatory T cells ( Tregs )