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CA2 — IL8

Text-mined interactions from Literome

Schorr et al., Eur J Immunol 1999 (Calcium Signaling) : Mechanisms of IL-8 induced Ca2+ signaling in human neutrophil granulocytes ... Here, we have measured IL-8 induced Ca2+ signals in single human neutrophil granulocytes using the Ca2+ indicator dye FURA-2 AM and we have investigated the signal transduction that leads to these Ca2+ signals with various pharmacological tools ... Our results indicate that IL-8 induced Ca2+ signals consist of at least two components ... This Ca2+ influx may prolong IL-8 induced Ca2+ signals during granulocyte activation
Virchow et al., Naunyn Schmiedebergs Arch Pharmacol 1999 : In contrast, IL-8 induced Ca2+ signals and O2- generation were independent of genotype
Liu et al., Proc Soc Exp Biol Med 2000 (Calcium Signaling) : Ca2+ release from intracellular stores was strongly stimulated by acetylcholine (ACh) and ATP, but not by norepinephrine ( NA ), epidermal growth factor (EGF), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNFalpha)
Yu et al., Inflamm Res 2001 (Adenocarcinoma...) : In this study, we characterize the effect of intracellular Ca2+ on interleukin-8 gene expression in T84 human colonic epithelial cells
Savkovic et al., Am J Physiol Gastrointest Liver Physiol 2001 (Inflammation...) : In contrast to Salmonella typhimurium, EPEC stimulated IkappaBalpha degradation and IL-8 expression did not require Ca2+
Inamura et al., Int Arch Allergy Immunol 2002 : IL-8 and its homologues showed chemotactic activity toward them in a dose dependent manner, and IL-8 induced a dose dependent rapid and transient increase in [Ca2+ ] i in the mast cells
Nozawa et al., Biochem Pharmacol 2002 : H. pylori induced IL-8 production is dominantly regulated by Ca2+/calmodulin signaling, and ERK plays an important role in signal transmission for the efficient activation of H. pylori induced NF-kappaB activity, resulting in IL-8 production
Krieger et al., J Immunol 1992 : IL-8 induced [ Ca2+ ] i changes and histamine release in IL-3 primed basophils were pertussis toxin sensitive
Liu et al., J Infect Dis 1992 : Recombinant interleukin-8 induces changes in cytosolic Ca2+ in human neutrophils
Söderblom et al., Scand J Infect Dis 2003 (Inflammation) : Specifically, the proinflammatory cytokine interleukin-6 (IL-6) and chemokine IL-8 were induced by HlyA induced Ca2+ oscillations
Rah et al., J Biol Chem 2005 : Activation of CD38 by interleukin-8 signaling regulates intracellular Ca2+ level and motility of lymphokine activated killer cells
Kim et al., Cytokine 2005 : Involvement of mitogen activated protein kinase and NF-kappaB activation in Ca2+ induced IL-8 production in human mast cells
Yuo et al., Blood 1991 : Interleukin-8 (IL-8) stimulated an increase in cytoplasmic-free Ca2+ ( [ Ca2+ ] i ) and intracellular pH ( pHi ) in parallel at low concentrations ( 0.5 to 5 ng/mL ), and stimulated O2- release and membrane depolarization in parallel at high concentrations ( 50 to 5,000 ng/mL )
Govindaraju et al., Respir Res 2008 (Cystic Fibrosis) : IL-8 ( 100 nM ) induced a peak Ca2+ release that was higher in control than in CF cells : 228 +/- 7 versus 198 +/- 10 nM ( p < 0.05 )
Wang et al., J Biol Chem 2009 (Calcium Signaling) : Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1 induced Ca2+ signaling
Kodama et al., Meikai Daigaku Shigaku Zasshi 1990 (Bone Resorption...) : Among several bioactive substances known as coupling factors, transforming growth factor-beta ( TGF-beta ), interleukin-1 (IL-1), and prostaglandin ( PG ) E1 and E2 increased not only the activity of alkaline phosphatase but also the rate of incorporation of 45Ca2+ into ROS 17/2.8 during a 3-day culture : the former two factors are known to be formed at the site where bone is resorbed, while PG 's are known as one of the factors involved in bone resorption
Kodama et al., Meikai Daigaku Shigaku Zasshi 1989 (Bone Resorption) : The effects of interleukin 1, transforming growth factor-beta ( coupling factors ), prostaglandin E1, and prostaglandin E2 on incorporation of 45Ca2+ and on alkaline phosphatase activity were studied using cultured ROS 17/2.8 cells, one of cell lines derived from rat osteosarcoma
Qiu et al., Biochem Pharmacol 1994 : In the present study, we investigated the effects of lymphokines [interleukin-4 (IL-4), interleukin-2 (IL-2) ] and other pharmacologic agents [ lipopolysaccharide (LPS), phorbol 12-myristate 13-acetate ( PMA ) ] on HTMT induced Ca2+ and IP responses in non rosetted cells
Thomas et al., J Immunol 1994 : Rabbit neutrophils mobilized intracellular Ca2+ in response to IL-8 and NAP-2 but not to GRO or PF4
Schöndorf et al., Biochem Biophys Res Commun 1993 : Protein kinase C regulates IL-8 and fMLP induced cytoplasmic Ca2+ increase in human granulocytes by receptor modulation measurements by flow cytometry
Bhattacharya et al., J Immunol 1997 : A Ca2+ dependent autoregulation of lipopolysaccharide induced IL-8 receptor expression in human polymorphonuclear neutrophils
Kumar et al., Int J Immunopharmacol 1997 : Effect of prolactin on nitric oxide and interleukin-1 production of murine peritoneal macrophages : role of Ca2+ and protein kinase C
Bhattacharya et al., Indian J Biochem Biophys 1997 (Bacterial Infections) : Addition of CaCl2 accelerated and depletion of Ca2+ inhibited the downregulation of the IL-8 receptor
Sanchez et al., J Immunol 1998 : The IL-8 induced Ca2+ response is desensitizing, since a second dose of IL-8 did not trigger a second calcium response
Watanabe et al., Life Sci 1998 (Acidosis) : These results suggest that Ca2+ dependent IL-8 is produced by astrocytes, but not neuronal cells, under acidosis, and that this production may be related to the process of cell dysfunction resulting from membrane destruction induced by acidosis
Van Dervort et al., J Leukoc Biol 1998 : IL-8 caused a rapid rise in [Ca2+ ] i that returned to baseline values by 20 min. Peak [ Ca2+ ] i transients in response to N-formyl-methionyl-leucyl-phenylalanine ( fMLP ) were unaltered in IL-8 primed compared with unprimed cells
Kuhns et al., J Immunol 1998 : Ca2+ dependent production and release of IL-8 in human neutrophils
Hauser et al., Shock 1998 (Calcium Signaling) : PMN [Ca2+ ] i responses to interleukin (IL)-8 and Growth Related Oncogene ( GRO ) -alpha were studied by fura-2-acetoxymethyl ester fluorescence with or without reincubation in autologous plasma just prior to study
Petering et al., Blood 1999 : In addition, and in contrast to neutrophils and lymphocytes, IL-8 did not induce a rapid and transient release of cytosolic free Ca2+ ( [ Ca2+ ] i ) in eosinophils, even after preincubation with TH1- and TH2-like cytokines