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APOB — B3GALT4
Text-mined interactions from Literome
Chatterjee et al., Indian J Biochem Biophys 1990
:
Thus, it is concluded that ( i ) various lipid components, sphingosine and serine present in LDL are not involved in the
LDL mediated suppression of
GalT-2 activity in normal PT cells, and ( ii ) stringent structural requirements in the phosphatidylcholine molecule are necessary to exert a time and concentration dependent stimulation of GalT-2 activity
Chatterjee et al., J Biol Chem 1988
(Hyperlipoproteinemia Type II) :
In contrast
LDL modified by reductive methylation ( M-LDL, 100 micrograms/ml )
stimulated the activity of
GalT-2 , approximately 3-fold
Chatterjee et al., Glycobiology 1996
:
On the other hand,
LDL suppressed the activity of
GalT-2 in these cells ... This effect resulted from
Ox-LDL mediated activation of
GalT-2 that produced lactosylceramide
Chatterjee et al., Arterioscler Thromb Vasc Biol 1998
(Arteriosclerosis) :
Interestingly, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol ( D-PDMP ), an inhibitor of GalT-2, can abrogate the
Ox-LDL mediated activation of
GalT-2 , the signal kinase cascade noted above, as well as cell proliferation