Gene interactions and pathways from curated databases and text-mining

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MTOR — SMAD3

Text-mined interactions from Literome

Song et al., EMBO J 2006 : Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5 mediated Smad3 activation
Chen et al., Zhonghua Xin Xue Guan Bing Za Zhi 2008 (Coxsackievirus Infections) : We investigated the role of mTOR signal transduction on viral myocarditis by observing the effect of mTOR inhibitor rapamycin on Smad 3 and collagen type I expression in rat myocardial fibroblasts infected with coxsackievirus B 3 ( CVB 3 )
Winbanks et al., J Cell Biol 2012 (Hypertrophy) : Expression of constitutively active Smad3 not only markedly prevented skeletal muscle growth induced by follistatin but also potently suppressed follistatin induced Akt/mTOR/S6K signaling