Leeper et al., Am J Physiol Heart Circ Physiol 2009
(Aortic Aneurysm, Abdominal...) :
Apelin stimulation of cultured macrophages significantly reduced MCP-1 and TNF-alpha mRNA levels relative to baseline ( 2.03- and 1.89-fold reduction, P < 0.03, respectively ) but did not affect intimal adhesion molecule expression or medial or adventitial cell cytokine production
Pan et al., J Card Fail 2010
(Cardiomyopathies...) :
In cultured rat peritoneal macrophages, apelin directly inhibited the production of monocyte chemoattractant protein 1 and interleukin-8 induced by lipopolysaccharide
Lu et al., Amino Acids 2012
:
Apelin-APJ induces ICAM-1, VCAM-1 and MCP-1 expression via NF-?B/JNK signal pathway in human umbilical vein endothelial cells