◀ Back to CDK2

CDK2 — PI3

Text-mined interactions from Literome

Eapen et al., Mol Cell Biol 2001 : Notably, the PI 3-kinase inhibitor, LY294002, completely blocked cytokine induced Cdk2 activation and cell growth in irradiated 32D cells but not in nonirradiated cells
Uttamsingh et al., J Biol Chem 2003 : UR2 infected CEF grown in nonadherent conditions displayed faster cell cycle progression than the control or the UR2 mutant infected cells, and this appeared to correlate with a PI 3-kinase dependent increase in cyclin A-associated Cdk2 activity ... In conclusion, we have adopted an experimental system enabling us to study the signaling pathways in cells grown under anchorage independent conditions and have identified matrix independent activation of PI 3-kinase and Stat3 signaling functions, as well as the PI 3-kinase dependent increase of cyclin A-associated Cdk2 kinase activity, to be critical for the Ros-PTK induced anchorage independent growth