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CDK2 — EZH2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: EZH2 — CDK2 (direct interaction, enzymatic study) Chen et al., Nat Cell Biol 2010*

Text-mined interactions from Literome

Lu et al., Cancer Res 2011 (Nasopharyngeal Neoplasms) : Mechanistic investigations revealed that miR-26a suppressed the expression of c-myc, the cyclin D3 and E2, and the cyclin dependent kinase CDK4 and CDK6 while enhancing the expression of CDK inhibitors p14(ARF) and p21 ( CIP1 ) in an EZH2 dependent manner
Wu et al., J Biol Chem 2011 : Here, we demonstrate that Ezh2 can be regulated by the cyclin dependent kinase , CDK1, which phosphorylates Ezh2 at threonines 345 and 487