Gene interactions and pathways from curated databases and text-mining

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FAS — MST1

Text-mined interactions from Literome

Vichalkovski et al., Curr Biol 2008 : NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis ... Fas receptor stimulation promoted direct phosphorylation and activation of NDR1/2 by the mammalian STE20-like kinase 1 (MST1) , a downstream effector of RASSF1A
Graves et al., EMBO J 1998 : CD95/Fas induced cleavage of Mst1 was blocked by the cysteine protease inhibitor ZVAD-fmk, the more selective caspase inhibitor DEVD-CHO and by the viral serpin CrmA