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BMP2 — TMED7
Text-mined interactions from Literome
Nakamura et al., Biochem Biophys Res Commun 2003
(Neuroblastoma) :
We found a significant accumulation of
p27 ( KIP1 ) in
response to
BMP2 , whereas the expression level of Skp2, which is required for ubiquitin dependent p27 ( KIP1 ) degradation, was decreased during this differentiation process
Sharov et al., Proc Natl Acad Sci U S A 2006
:
Primary epidermal keratinocytes ( KC ) from TG mice exhibit significantly increased proliferation and decreased p27 ( Kip1 ) expression, compared with WT KC. Alternatively, activation of
BMP signaling in HaCaT KC induces growth arrest, stimulates p27 ( Kip1 ) expression, and positively
regulates p27 ( Kip1 ) promoter activity, thus further supporting a role of p27 ( Kip1 ) in mediating the effects of BMP signaling on HF size