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ARG1 — TNF
Text-mined interactions from Literome
Moinard et al., J Leukoc Biol 2000
:
GLN,
ARG , and OKG all
restored TNF-alpha secretion by macrophages of glucocorticoid treated rats
Meszaros et al., J Immunol 2000
:
Mphi induced apoptosis was inhibited by peptide
Arg-Gly-Asp-Ser , anti-beta3 ( CD61 ) Ab, CD36 peptide, or anti-TNF-alpha Ab. Soluble
TNF-alpha did not
induce PMN apoptosis
Zhang et al., Clin Exp Allergy 2005
(Asthma...) :
Actinomycin D abolished and dexamethasone concentration-dependently suppressed the
TNF-alpha induced enhancement of the
des-Arg9-bradykinin and bradykinin responses
Ckless et al., Am J Respir Cell Mol Biol 2007
:
Our results demonstrate that reduction of
arginase activity enhanced cellular content of NO and S-nitrosated proteins, and
resulted in decreases in
TNF-alpha- or LPS stimulated NF-kappaB DNA binding and transcriptional activity, in association with enhanced S-nitrosation of p50
Gao et al., Arterioscler Thromb Vasc Biol 2007
(Disease Models, Animal...) :
Our data demonstrate
TNF-alpha upregulates expression of
arginase in endothelial cells, which leads to O2 ( - ) production then induces endothelial dysfunction in I/R injury
Grenier et al., Toxins 2010
:
Both
Arg- and Lys-gingipain preparations
induced the secretion of
TNF-a and IL-8 by macrophages
Thakur et al., Journal of translational medicine 2013
(Pancreatic Neoplasms) :
Reduced accumulation of MDSC was accompanied by significantly lower levels of COX2 ( p < 0.0048 ), PGE2 ( p < 0.03 ), and their downstream effector molecule
Arginase-1 ( p < 0.01 ), and significantly higher levels of
TNF-a , IL-12 and chemokines CCL3, CCL4, CCL5, CXCL9 and CXCL10 under aATC
induced Th1 cytokine enriched microenvironment