Masuno et al., J Lipid Res 2002
:
The presence of BPA during the same period caused a 150 % increase in the TG content, a 60 % increase in the LPL activity, and a 500 % increase in the GPDH activity ... The simultaneous presence of BPA with INS caused a 370 % increase in the TG content, a 200 % increase in the LPL activity, and a 225 % increase in the GPDH activity compared with the cultures treated with INS alone
Masuno et al., Toxicological sciences : an official journal of the Society of Toxicology 2005
:
LY294002, a chemical inhibitor of phosphatidylinositol 3-kinase ( PI 3-kinase ), blocked completely the increasing effect of BPA on TG accumulation and expression of LPL and aP2 mRNAs